Linkage Analysis in the Next-Generation Sequencing Era
نویسندگان
چکیده
منابع مشابه
Linkage analysis in the next-generation sequencing era.
Linkage analysis was developed to detect excess co-segregation of the putative alleles underlying a phenotype with the alleles at a marker locus in family data. Many different variations of this analysis and corresponding study design have been developed to detect this co-segregation. Linkage studies have been shown to have high power to detect loci that have alleles (or variants) with a large ...
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ژورنال
عنوان ژورنال: Human Heredity
سال: 2011
ISSN: 1423-0062,0001-5652
DOI: 10.1159/000334381